Pump 40

PUMP-40
Pantoprazole 40mg Tablet
  • Mode of action

    • A proton pump inhibitor (PPI)
    • Act by irreversibly blocking the hydrogen/potassium adenosine triphosphatase enzyme system (the H+/K+ ATPase) of the gastric parietal cells, which is the terminal step in acid production
    • Significantly more effective than H2 antagonists
    • Used to treat gastroesophageal reflux disease (GERD), a condition that causes gastric juices to flow upward from the stomach and into the esophagus
    • Also treats conditions in which the stomach makes excess acid, including Zollinger-Ellison syndrome

  • Indication

    • Reflux Esophagitis: 40mg OD for 4-8weeks
    • GERD or heartburn: 40mg OD for 4-8weeks
    • Duodenal (intestinal) ulcers: 40mg OD
    • Gastric (stomach) ulcers: 40mg OD for 4-8wks
    • pylori infection: 40mg BD for 7 days
    • Zollinger-Ellison syndrome: 40mg BD
    • Stomach ulcers associated with NSAID use: 20mg OD

  • Dose

    • Reflux Esophagitis: 40mg OD for 4-8weeks
    • GERD or heartburn: 40mg OD for 4-8weeks
    • Duodenal (intestinal) ulcers: 40mg OD
    • Gastric (stomach) ulcers: 40mg OD for 4-8wks
    • H. pylori infection: 40mg BD for 7 days
    • Zollinger-Ellison syndrome: 40mg BD
    • Stomach ulcers associated with NSAID use: 20mg OD