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Azithromycin 250 - 500mg Tablet
  • Mode of action

    • An azalide, a subclass of macrolide antibiotic
    • More potent against certain bacterial species than erythromycin
    • Prevents bacteria from growing by interfering with their protein synthesis. It binds to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.
    • Has broad spectrum. It inhibits some Gram-(+) bacteria, some Gram-(-) bacteria, and many atypical bacteria
    • Has widespread popularity arises primarily from its slow elimination from the body, which allows many infections to be treated with 3-5 days of once-daily administration, compared to 3-4 times a day for up to 2 weeks for erythromycin

  • Indication

    • Pharyngitis
    • Tonsillitis
    • Pneumonia
    • Bronchitis
    • Sinusitis
    • Ear infections
    • Genital tract infections
    • Skin and soft tissue infections

  • Dose

    Skin and soft tissue infections

      • Adult: 500 mg once daily for 3 days. Alternatively, 500 mg as a single dose on the 1st day followed by 250 mg once daily for 4 days.
      • Child: >6 month: 10 mg/kg; 15-25 kg: 200 mg; 26-35 kg: 300 mg; 36-45 kg: 400 mg. Doses to be taken once daily for 3 days

    Respiratory tract infections

      • Adult: 500 mg once daily for 3 days. Alternatively, 500 mg as a single dose on the 1st day followed by 250 mg once daily for 4 days.
      • Child: >6 month: 10 mg/kg; 15-25 kg: 200 mg; 26-35 kg: 300 mg; 36-45 kg: 400 mg. Doses to be taken once daily for 3 days

    Uncomplicated genital infections due to Chlamydia trachomatis
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        • Adult: 1 g as a single dose.

    Uncomplicated gonorrhoea
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    • Adult: 2 g as a single dose