Myodip
Amlodipine (as besilate) 2.5, 5 & 10mg
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Mode of action
It is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle, results in smooth muscle relaxation.
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Indication
- Hypertension
- Angina pectoris
- Prinzmetal’s Angina (Vasospastic)
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Side effects
Headache, peripheral oedema, flushing, hypotension, bradycardia, dizziness
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Precaution
CHF, elderly, children, pregnancy, lactation and hypertrophic cardiomyopathy
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Dose
Hypertension, Prinzmetal’s Angina, Stable angina
Adult: 5mg once daily increased to 10mg once daily if necessary. Elderly: initial dose 2.5 once daily