Amlodipine (as besilate) 2.5, 5 & 10mg
  • Mode of action

    It is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle, results in smooth muscle relaxation.

  • Indication

    • Hypertension
    • Angina pectoris
    • Prinzmetal’s Angina (Vasospastic)

  • Side effects

    Headache, peripheral oedema, flushing, hypotension, bradycardia, dizziness

  • Precaution

    CHF, elderly, children, pregnancy, lactation and hypertrophic cardiomyopathy

  • Dose

    Hypertension, Prinzmetal’s Angina, Stable angina
    Adult: 5mg once daily increased to 10mg once daily if necessary. Elderly: initial dose 2.5 once daily