Nextra

Traxenamic Acid 250 - 500mg Cap
  • Mode of action

    It is an analogue of amino acid lysine, binds to the lysine binding site on plasminogen and prevents its combination with fibrin.

  • Indication

    • Overdose of fibrinolytics
    • After cardiac-pulmonary bypass surgery
    • Tooth extraction
    • Menorrhagia
    • Ocular trauma
    • Bleeding of peptic ulcer

  • Side effects

    Dizziness, hypotension, thrombosis, nausea, vomiting, visual abnormality

  • Precaution

    Hypersensitivity, renal impairment, active intravascular clotting, pregnancy

  • Dose

    Short term management of hemorrhage
    Adult: 1-1.5g or 15-25mg/kg bid or tid
    Child: 25mg/kg bid or tid

    Management of hereditary angioedema
    Adult: 0.5-1g or 10mg/kg tid or 25-50mg/kg daily br continuous infusion
    Child: 10mg/kg bid or tid