Nextra
Traxenamic Acid 250 - 500mg Cap
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Mode of action
It is an analogue of amino acid lysine, binds to the lysine binding site on plasminogen and prevents its combination with fibrin.
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Indication
- Overdose of fibrinolytics
- After cardiac-pulmonary bypass surgery
- Tooth extraction
- Menorrhagia
- Ocular trauma
- Bleeding of peptic ulcer
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Side effects
Dizziness, hypotension, thrombosis, nausea, vomiting, visual abnormality
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Precaution
Hypersensitivity, renal impairment, active intravascular clotting, pregnancy
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Dose
Short term management of hemorrhage
Adult: 1-1.5g or 15-25mg/kg bid or tid
Child: 25mg/kg bid or tidManagement of hereditary angioedema
Adult: 0.5-1g or 10mg/kg tid or 25-50mg/kg daily br continuous infusion
Child: 10mg/kg bid or tid