OHM-20

Omeprazole 20 mg tablet
  • Mode of action

    OHM is a substitutes benzimidazole gastric anti secretory agent and is also known as PPI. It blocks the final step in gastric acid selection by specific inhibition of H+/K+ATPase enzyme, which is present on the surface of the gastric parietal cell.

  • Indication

    • Peptic ulcer
    • pylori infection
    • Gastro-oesophageal reflux diseases
    • Zollinger Ellison syndrome
    • Oesophagitis
    • Acid related dyspepsia
    • NSAID associated ulceration

  • Dose

    Usual Adult Dose for Gastric Ulcer

    40 mg orally once a day
    -Duration of therapy: 4 to 8 weeks

    Use: Short-term treatment of active benign gastric ulcer

    Usual Adult Dose for Erosive Esophagitis

    Treatment: 20 mg orally once a day
    -Duration of therapy: 4 to 8 weeks

    Maintenance: 20 mg orally once a day

    Usual Adult Dose for Duodenal Ulcer

    20 mg orally once a day
    -Duration of therapy: 4 weeks

    Use: Short-term treatment of active duodenal ulcer

    Usual Adult Dose for Helicobacter pylori Infection

    Dual therapy: 40 mg orally once a day, taken concomitantly with clarithromycin
    -Duration of therapy: 14 days

    Usual Adult Dose for Zollinger-Ellison Syndrome

    Initial dose: 60 mg orally once a day
    Maximum dose: 360 mg/day (as 120 mg orally 3 times a day)

    Usual Adult Dose for Gastroesophageal Reflux Disease

    20 mg orally once a day
    -Duration of therapy: Up to 4 weeks

    Use: Treatment of heartburn and other symptoms associated with GERD

    Usual Adult Dose for Dyspepsia

    Over-the-Counter (OTC) formulations: 20 mg orally once a day in the morning
    -Duration of therapy: 14 days