Ofloxacin USP 200 - 400mg
  • Indication

    • A second-generation, synthetic antibiotic of fluoroquinolone class
    • A broad-spectrum antibiotic that is active against both Gram-positive and Gram negative bacteria
    • Stops the multiplication of bacteria by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, which is an enzyme necessary to separate (mostly in prokaryotes, in bacteria in particular) replicated DNA, thereby inhibiting bacterial cell division.

  • Dose

    • Normal Dose is 200 – 400 mg 12 hourly
    • Acute bacterial exacerbations of chronic bronchitis: 400 mg BID 7-10 days
    • Community-acquired Pneumonia: 400 mg BID 7-10 days
    • Uncomplicated skin and skin structure infections: 400 mg BID for 10 days
    • Acute, uncomplicated urethral and cervical gonorrhea: 400mg single dose.
    • Acute pelvic inflammatory disease: 400 mg BID 10-14 days.
    • Uncomplicated cystitis: 200 mg BID
    • Complicated urinary tract infections: 200 mg BID for 3-10 days