Sunolol
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Mode of action
It is a β blocker antihypertensive agent. It competes sympathomimetic neurotransmitters such as catecholamines for binding at beta (1)-adrenergic receptors in the heart and vascular smooth muscle, inhibiting sympathetic stimulation. This results in a reduction in heart rate, cardiac output, systolic and diastolic blood pressure, and reflex orthostatic hypotension.
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Indication
- Hypertension
- Angina pectoris
- Prophylaxis of migraine
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Side effects
Brochospasm, fatigue, dizziness, insomnia, lethargy, nightmare, impotence, hypotension and depression
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Precaution
Peripheral vascular disease, DM, Acute MI, Variant angina
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Dose
Hypertension,
Adult: 25-100mg daily as a single dose depending upon the response.Angina pectoris,
Adult: 50-100mg daily given as a single dose or divided dose. Max dose 200mg dailyProphylaxis of migraine,
Adult: 50-100mg daily